DERMATOLOGIC SURGERY Extramammary Paget’s disease: Surgical treatment with Mohs micrographic surgery
نویسندگان
چکیده
Results: The recurrence rate after treatment with MMS was 16% for primary EMPD and 50% for recurrent EMPD. The 5-year tumor-free rates (Kaplan-Meier analysis) were 80% for primary tumors and 56% for recurrent tumors. Using MMS, the salvage rate (and, hence, overall cure rate) was 100%. Margins of 5 cm were required to clear 97% of the tumors. The recurrence rate after non-MMS ( from the literature) is 33% to 60%.
منابع مشابه
Surgical treatment of Paget’s disease of the vulva using Mohs micrographic surgery, followed by vulvar reconstruction using the “lotus petal” suprafascial flap
Vulvar Paget’s disease is an extramammary manifestation of Paget’s disease, a cutaneous neoplasm that clinically appears as sharply defined erythematous plaques with irregular borders that usually affect apocrine gland-bearing skin. Extramammary Paget’s disease (EMPD) of the vulva can remain undiagnosed for years and could be associated with multifocal neoplasms. The current gold standard for t...
متن کاملMohs micrographic surgery for deeply penetrating, expanding benign cutaneous neoplasms.
The indications for MMS include malignant tumors with poorly defined borders, histology, tumor size, level of invasion, anatomic location, reduced patient immunity, and recurrence after previous treatment. MMS is indicated for locally aggressive tumors that are difficult to eradicate by routine measures and recurrent tumors following conventional surgical excision. MMS has been used successfull...
متن کاملTreatment of malignant fibrous histiocytoma and atypical fibrous xanthomas with micrographic surgery.
Fibrous tumors of the soft tissue are usually benign, but some fibrous neoplasms such as dermatofibrosarcoma protuberans (DFSP), atypical fibroxanthoma (AFX), and malignant fibrohistiocytoma (MFH) can be very destructive locally with a high recurrence rate after local excision. On occasion, they can metastasize. Previous reports have confirmed the high success rate of Mohs micrographic surgery ...
متن کاملExtramammary Paget's disease: surgical treatment with Mohs micrographic surgery.
BACKGROUND Extramammary Paget's disease (EMPD) is an uncommon tumor that has a high rate of recurrence after conventional surgical treatments. OBJECTIVE Our purpose was to establish the efficacy of Mohs micrographic surgery (MMS) in the treatment of EMPD, and to make treatment recommendations with regard to surgical margins. We also attempted to summarize the published recurrence rates of EMP...
متن کاملDeep venous thrombosis following Mohs micrographic surgery: case report.
Deep venous thrombosis (DVT) of the lower extremity is a common adverse outcome following large surgical procedures on the lower extremities, such as orthopedic surgery. It is a much rarer occurrence following Mohs micrographic surgery especially when patients have not immobilized the extremity. Reports of postoperative thrombotic or thromboembolic disease in the dermatologic literature are spa...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
دوره شماره
صفحات -
تاریخ انتشار 2004